We offer custom assay development for a wide range of project needs. Our scientists work diligently to understand your drug discovery project and offer comprehensive strategies towards developing robust assays.
Examples of applications include:
- Protease assays
- Cell cytotoxicity assay
- Protein and DNA quantification
- Molecular Beacons
Figure 1. A full titration series of a compound of interest and model compound were tested against a therapeutic enzymatic target. Selectivity was assessed using enzymes from similar and distant families. Compound X was verified for purity and correct molecular weight using TSQ Quantum Triple Quadrupole LC-MS. Enzymes are assayed in the linear dynamic range so that a titration series of a model compound yields predictable and robust inhibition effects.
To get started with Assay Development, contact us so we can discuss your specific project or idea!
Typical assays include:
- Enzyme activity, drug inhibition and selectivity profiling
- ELISA development
- tr-FRET interaction assays
- In-cell fluorescence