full
image
#666666
https://avmbiomed.com/wp-content/themes/smartbox-installable/
https://avmbiomed.com/
#26ade4
style3
844.286.2466

Targeted Interaction

smart-topphoto-short

 

Targeted Interaction Studies/Surface Plasmon Resonance

 

For purposes of identifying novel protein interactions (whether with DNA, protein, antibody, or chemical compound), our 20,000-member human protein array is unmatched in sensitivity and breadth of coverage.  However, the array is not the ideal tool for detailed study of known or suspected interactions.  There are several available tools for this type of study, but none with the combined advantages of Surface Plasmon Resonance (SPR):

 

  • Highly sensitive
  • Label-free detection
  • Real-time monitoring
  • Quantitative
  • Provides kinetic rate constants
  • Consumes low volume of sample
  • Easy to perform = cost effective

AVMBioMed utilizes a fully-automated BI-4500 5-Channel SPR System (Biosensing Instrument) with BI-DirectFlowTM technology that enables precision sample delivery and zero dispersion for higher quality results.

 

Targeted Image
Wide dynamic range (>10-5)

Binding constants down to pM-1 

Precision temperature control (6-50oC) for thermodynamic studies 

Broad response time (4ms to hours)


Materials needed for SPR service:

  • 50 µg protein
  • Molecular weight(s)
  • Concentration of sample



Deliverables: 

Within 2 weeks (typical project)we provide a sensorgram of protein interaction and a summary of the kinetic data (ka, kd, kD).

paged
Loading posts...
link_magnifier
#6E787E
on
fadeInUp
loading
off